science education

Exploring Nature Science Education Resource:

Life Science, Earth Science, and Physical Science Resources for K-12

DNA Transcription and Translation Activity (Middle School and Up)

DNA Transcription and Translation

Organisms are made up of proteins that are, in turn, made up of amino acids. The amino acids needed for protein synthesis by each organism is encoded in their DNA. Using the processes of transcription and translation, you can, theoretically start with a strand of DNA and calculate the amino acid chains for which an organism is coded.

In this activity, students will be given three strands of DNA. Using the different resources provided, they will determine the amino acids for which the DNA is coding and the organisms that would result from their protein synthesis.

Resources Needed:
1. Transcription to Protein Synthesis sheet
2. Genetic Code chart
3. Amino Acid Building Blocks of Organisms chart

1. Examine the three strands of DNA provided.
2. Transcription: On the worksheet, make the DNA strand into mRNA codons (review Transcription to Protein Synthesis sheet).
3. Translation: On the worksheet, make the mRNA codons into tRNA codons (review Transcription to Protein Synthesis sheet).
3. Amino Acid Chains: Using the Genetic Code chart, fill in the amino acids for each DNA strand.
4. Organisms: Using the to Amino Acid Building Blocks of Organisms chart, find which three organisms you have decoded.
5. In the last step, can you speculate what these three organisms represent?

DNA Transcription - Translation Worksheet
Transcription to Protein Synthesis Chart
The Genetic Code - Chart
Amino Acid Building Blocks of Organisms

Fulfillment of Next Generation Science Standards (NGSS)

Next Generation Science Standards:
Disciplinary Core Ideas
LS1.A: Structure and Functions
• All cells contain genetic information in the form of DNA molecules. Genes are regions in the DNA that contain the instructions that code for the formation of proteins.

Performance Expectations - Students who demonstrate understanding can:
HS-LS3-1. Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring.

Citing Research References

When you research information you must cite the reference. Citing for websites is different from citing from books, magazines and periodicals. The style of citing shown here is from the MLA Style Citations (Modern Language Association).

When citing a WEBSITE the general format is as follows.
Author Last Name, First Name(s). "Title: Subtitle of Part of Web Page, if appropriate." Title: Subtitle: Section of Page if appropriate. Sponsoring/Publishing Agency, If Given. Additional significant descriptive information. Date of Electronic Publication or other Date, such as Last Updated. Day Month Year of access < URL >.

Here is an example of citing this page:

Amsel, Sheri. "DNA Transcription and Translation Activity (Middle School and Up)" Exploring Nature Educational Resource ©2005-2019. October 19, 2019
< > has more than 2,000 illustrated animals. Read about them, color them, label them, learn to draw them.

cheetah, tiger, panda, fox, bear, cougar