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Recombination - Creating More Genetic Variation

The chromosomes we inherit from are parents are not exact copies. They experience recombination — where pieces of genetic material are swapped from matching chromosomes to form new mixtures of genes. This produces traits that may not have been in either parent. Unequal swapping of genes may cause many diseases.

The differences between human genomes are small, but small changes in the code, called single nucleotide polymorphisms (SNPs or “snips”), if they occur in a protein sequencing area, can produce different proteins then the body intended. This can have an effect on biological function.

Mapping the most common SNPs in the human genome is one of the most immediate benefits of Human Genome Project. SNPs or “snips” are found along the chromosome at about 1 every 600-1,000 basepairs. They seem to appear in groups called, “Haplotype Blocks.” It is believed that the genome may have as many as 180, 000 haplotype blocks of SNPs.

Recombination - Creating More Genetic Variation
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